In hopes of helping others I wanted to post my troubleshooting today . (OK I should be working on 'real" stuff, but the Mac is stress relief ;)

On my SuperMac accelerated SE running System 6.0.8 with my Internal SCSI2SD 5.2, the PPP Control Panel crashed the mac on "Soft Close" so that the SCSI2SD 6.0.8 image would not longer boot (Flashing disk question).
I was able to boot off my Floppy EMU with System Tools. The internal SCSI2SD drive mounted without an issue, and Disk First Aid 7.2.2 report no errors on the drive. I attempted to bless the system folder by dragging the system file out and dragging it back into the System Folder, double checking the Start Up disk Control Panel, but upon reboot -nope - same flashing question mark when attempting to boot off of internal.
I eventually fixed it by copying over the system file from System 6.0.8 on my SCSI2SD 5.5 External and replacing the system file on the Internal SCSI2SD.
This fixed things, so I think the System file was somehow corrupted. Just posting this here in case anyone else has a similar issue.

I guess I better back up that SCSI2SD image!

You may be able to prevent this from happening in the future with a tweak to your SCSI2SD settings. In case you haven't already, make sure you have "Enable Disk Cache" disabled.

>> Branchus said:

You may be able to prevent this from happening in the future with a tweak to your SCSI2SD settings. In case you haven't already, make sure you have "Enable Disk Cache" disabled. Click to expand...

Excellent! Thanks so much.

Update - I verified the cache setting in the SCSI2SD firmware. It was not enabled so that was not the culprit, but here's the setting to ensure this is documented for others.